| C21 | 121 | Living Lore | Creature — Avatar | | |
| C21 | 122 | Metallurgic Summonings | Enchantment | | |
| C21 | 123 | Mind's Desire | Sorcery | | |
| C21 | 124 | Naru Meha, Master Wizard | Legendary Creature — Human Wizard | | |
| C21 | 125 | Ponder | Sorcery | | |
| C21 | 126 | Rapid Hybridization | Instant | | |
| C21 | 127 | Reef Worm | Creature — Worm | | |
| C21 | 128 | Rite of Replication | Sorcery | | |
| C21 | 129 | Serum Visions | Sorcery | | |
| C21 | 130 | Swarm Intelligence | Enchantment | | |
| C21 | 131 | Talrand, Sky Summoner | Legendary Creature — Merfolk Wizard | | |
| C21 | 132 | Traumatic Visions | Instant | | |
| C21 | 133 | Treasure Cruise | Sorcery | | |
| C21 | 134 | Ambition's Cost | Sorcery | | |
| C21 | 135 | Ancient Craving | Sorcery | | |
| C21 | 136 | Bloodthirsty Aerialist | Creature — Vampire Rogue | | |
| C21 | 137 | Bloodtracker | Creature — Vampire Wizard | | |
| C21 | 138 | Curse of Disturbance | Enchantment — Aura Curse | | |
| C21 | 139 | Damnable Pact | Sorcery | | |
| C21 | 140 | Deadly Tempest | Sorcery | | |
| C21 | 141 | Deathbringer Regent | Creature — Dragon | | |
| C21 | 142 | Defiant Bloodlord | Creature — Vampire | | |
| C21 | 143 | Epicure of Blood | Creature — Vampire | | |
| C21 | 144 | Feed the Swarm | Sorcery | | |
| C21 | 145 | Greed | Enchantment | | |
| C21 | 146 | Infernal Offering | Sorcery | | |
| C21 | 147 | Necropolis Regent | Creature — Vampire | | |
| C21 | 148 | Noxious Gearhulk | Artifact Creature — Construct | | |
| C21 | 149 | Ob Nixilis Reignited | Legendary Planeswalker — Nixilis | | |
| C21 | 150 | Parasitic Impetus | Enchantment — Aura | | |
| C21 | 151 | Reckless Spite | Instant | | |
| C21 | 152 | Sangromancer | Creature — Vampire Shaman | | |
| C21 | 153 | Sanguine Bond | Enchantment | | |
| C21 | 154 | Silversmote Ghoul | Creature — Zombie Vampire | | |
| C21 | 155 | Suffer the Past | Instant | | |
| C21 | 156 | Taste of Death | Sorcery | | |
| C21 | 157 | Vampire Nighthawk | Creature — Vampire Shaman | | |
| C21 | 158 | Apex of Power | Sorcery | | |
| C21 | 159 | Blasphemous Act | Sorcery | | |
| C21 | 160 | Brass's Bounty | Sorcery | | |
| C21 | 161 | Chain Reaction | Sorcery | | |
| C21 | 162 | Charmbreaker Devils | Creature — Devil | | |
| C21 | 163 | Combustible Gearhulk | Artifact Creature — Construct | | |
| C21 | 164 | Daretti, Scrap Savant | Legendary Planeswalker — Daretti | | |
| C21 | 165 | Dualcaster Mage | Creature — Human Wizard | | |
| C21 | 166 | Erratic Cyclops | Creature — Cyclops Shaman | | |
| C21 | 167 | Etali, Primal Storm | Legendary Creature — Elder Dinosaur | | |
| C21 | 168 | Faithless Looting | Sorcery | | |
| C21 | 169 | Feldon of the Third Path | Legendary Creature — Human Artificer | | |
| C21 | 170 | Fiery Fall | Instant | | |
| C21 | 171 | Hellkite Igniter | Creature — Dragon | | |
| C21 | 172 | Hellkite Tyrant | Creature — Dragon | | |
| C21 | 173 | Hoard-Smelter Dragon | Creature — Dragon | | |
| C21 | 174 | Humble Defector | Creature — Human Rogue | | |
| C21 | 175 | Jaya Ballard | Legendary Planeswalker — Jaya | | |
| C21 | 176 | Mana Geyser | Sorcery | | |
| C21 | 177 | Pia Nalaar | Legendary Creature — Human Artificer | | |
| C21 | 178 | Quicksmith Genius | Creature — Human Artificer | | |
| C21 | 179 | Seething Song | Instant | | |
| C21 | 180 | Sunbird's Invocation | Enchantment | | |