| SPE | 1 | Amateur Hero | Creature — Human Hero | | |
| SPE | 2 | Amazing Alliance | Enchantment | | |
| SPE | 3 | MJ, Rising Star | Legendary Creature — Human Performer | | |
| SPE | 4 | Spider-Man, Peter Parker | Legendary Creature — Spider Human Hero | | |
| SPE | 5 | Alchemax Slayer-Bots | Artifact Creature — Robot Villain | | |
| SPE | 6 | Future Flight | Enchantment — Aura | | |
| SPE | 7 | Lyla, Holographic Assistant | Legendary Artifact Creature — Illusion Advisor | | |
| SPE | 8 | Spider-Man 2099, Miguel O'Hara | Legendary Creature — Spider Human Hero | | |
| SPE | 9 | Grendel, Spawn of Knull | Legendary Creature — Symbiote Dragon Villain | | |
| SPE | 10 | Lethal Protection | Sorcery | | |
| SPE | 11 | Symbiote Spawn | Creature — Symbiote Villain | | |
| SPE | 12 | Venom, Eddie Brock | Legendary Creature — Symbiote Villain | | |
| SPE | 13 | Double Trouble | Instant | | |
| SPE | 14 | Ghost-Spider, Gwen Stacy | Legendary Creature — Spider Human Hero | | |
| SPE | 15 | The Mary Janes | Legendary Creature — Human Bard Performer | | |
| SPE | 16 | Rampaging Classmate | Creature — Lizard Berserker | | |
| SPE | 17 | Prowler, Misguided Mentor | Legendary Creature — Human Rogue Villain | | |
| SPE | 18 | Spider-Man, Miles Morales | Legendary Creature — Spider Human Hero | | |
| SPE | 19 | Twisted Spider-Clone | Creature — Spider Human | | |
| SPE | 20 | Venom Blast | Sorcery | | |
| SPE | 21 | Grasping Tentacles | Sorcery | | |
| SPE | 22 | Venom, Deadly Devourer | Legendary Creature — Symbiote Villain | | |
| SPE | 23 | Green Goblin, Nemesis | Legendary Creature — Goblin Human Villain | | |
| SPE | 24 | Doc Ock, Evil Inventor | Legendary Creature — Human Scientist Villain | | |
| SPE | 25 | Sensational Spider-Man | Legendary Creature — Spider Human Hero | | |
| SPE | 26 | Pumpkin Bombs | Artifact | | |