| C21 | 301 | Memorial to Genius | Land | | |
| C21 | 302 | Mikokoro, Center of the Sea | Legendary Land | | |
| C21 | 303 | Mosswort Bridge | Land | | |
| C21 | 304 | Myriad Landscape | Land | | |
| C21 | 305 | Novijen, Heart of Progress | Land | | |
| C21 | 306 | Opal Palace | Land | | |
| C21 | 307 | Oran-Rief, the Vastwood | Land | | |
| C21 | 308 | Orzhov Basilica | Land | | |
| C21 | 309 | Phyrexia's Core | Land | | |
| C21 | 310 | Radiant Fountain | Land | | |
| C21 | 311 | Reliquary Tower | Land | | |
| C21 | 312 | Rogue's Passage | Land | | |
| C21 | 313 | Sapseep Forest | Land — Forest | | |
| C21 | 314 | Scavenger Grounds | Land — Desert | | |
| C21 | 315 | Secluded Steppe | Land | | |
| C21 | 316 | Shivan Reef | Land | | |
| C21 | 317 | Simic Growth Chamber | Land | | |
| C21 | 318 | Slayers' Stronghold | Land | | |
| C21 | 319 | Sunhome, Fortress of the Legion | Land | | |
| C21 | 320 | Tainted Field | Land | | |
| C21 | 321 | Tainted Wood | Land | | |
| C21 | 322 | Temple of Epiphany | Land | | |
| C21 | 323 | Temple of Malady | Land | | |
| C21 | 324 | Temple of Mystery | Land | | |
| C21 | 325 | Temple of Silence | Land | | |
| C21 | 326 | Temple of the False God | Land | | |
| C21 | 327 | Temple of Triumph | Land | | |
| C21 | 328 | Breena, the Demagogue | Legendary Creature — Bird Warlock | | |
| C21 | 329 | Felisa, Fang of Silverquill | Legendary Creature — Vampire Wizard | | |
| C21 | 330 | Veyran, Voice of Duality | Legendary Creature — Efreet Wizard | | |
| C21 | 331 | Zaffai, Thunder Conductor | Legendary Creature — Human Shaman | | |
| C21 | 332 | Gyome, Master Chef | Legendary Creature — Troll Warlock | | |
| C21 | 333 | Willowdusk, Essence Seer | Legendary Creature — Dryad Druid | | |
| C21 | 334 | Alibou, Ancient Witness | Legendary Artifact Creature — Golem | | |
| C21 | 335 | Osgir, the Reconstructor | Legendary Creature — Giant Artificer | | |
| C21 | 336 | Adrix and Nev, Twincasters | Legendary Creature — Merfolk Wizard | | |
| C21 | 337 | Esix, Fractal Bloom | Legendary Creature — Fractal | | |
| C21 | 338 | Angel of the Ruins | Artifact Creature — Angel | | |
| C21 | 339 | Archaeomancer's Map | Artifact | | |
| C21 | 340 | Bronze Guardian | Artifact Creature — Golem | | |
| C21 | 341 | Combat Calligrapher | Creature — Bird Cleric | | |
| C21 | 342 | Digsite Engineer | Creature — Dwarf Artificer | | |
| C21 | 343 | Excavation Technique | Sorcery | | |
| C21 | 344 | Guardian Archon | Creature — Archon | | |
| C21 | 345 | Losheel, Clockwork Scholar | Legendary Creature — Elephant Artificer | | |
| C21 | 346 | Monologue Tax | Enchantment | | |
| C21 | 347 | Nils, Discipline Enforcer | Legendary Creature — Human Cleric | | |
| C21 | 348 | Promise of Loyalty | Sorcery | | |
| C21 | 349 | Scholarship Sponsor | Creature — Human Advisor | | |
| C21 | 350 | Commander's Insight | Instant | | |
| C21 | 351 | Curiosity Crafter | Creature — Bird Wizard | | |
| C21 | 352 | Dazzling Sphinx | Creature — Sphinx | | |
| C21 | 353 | Deekah, Fractal Theorist | Legendary Creature — Human Wizard | | |
| C21 | 354 | Inspiring Refrain | Sorcery | | |
| C21 | 355 | Muse Vortex | Sorcery | | |
| C21 | 356 | Octavia, Living Thesis | Legendary Creature — Elemental Octopus | | |
| C21 | 357 | Perplexing Test | Instant | | |
| C21 | 358 | Replication Technique | Sorcery | | |
| C21 | 359 | Sly Instigator | Creature — Human Wizard | | |
| C21 | 360 | Spawning Kraken | Creature — Kraken | | |