| SPM | 61 | Prison Break | Sorcery | | |
| SPM | 62 | Risky Research | Sorcery | | |
| SPM | 63 | Sandman's Quicksand | Sorcery | | |
| SPM | 64 | Scorpion, Seething Striker | Legendary Creature — Scorpion Human Villain | | |
| SPM | 65 | Scorpion's Sting | Instant | | |
| SPM | 66 | The Soul Stone | Legendary Artifact — Infinity Stone | | |
| SPM | 67 | Spider-Man Noir | Legendary Creature — Spider Human Hero | | |
| SPM | 68 | The Spot's Portal | Instant | | |
| SPM | 69 | Swarm, Being of Bees | Legendary Creature — Insect Villain | | |
| SPM | 70 | Tombstone, Career Criminal | Legendary Creature — Human Villain | | |
| SPM | 71 | Venom, Evil Unleashed | Legendary Creature — Symbiote Villain | | |
| SPM | 72 | Venomized Cat | Creature — Symbiote Cat Villain | | |
| SPM | 73 | Venom's Hunger | Sorcery | | |
| SPM | 74 | Villainous Wrath | Sorcery | | |
| SPM | 75 | Angry Rabble | Creature — Human Citizen | | |
| SPM | 76 | Electro, Assaulting Battery | Legendary Creature — Human Villain | | |
| SPM | 77 | Electro's Bolt | Sorcery | | |
| SPM | 78 | Gwen Stacy // Ghost-Spider | Legendary Creature — Human Performer Hero | | |
| SPM | 79 | Heroes' Hangout | Sorcery | | |
| SPM | 80 | Hobgoblin, Mantled Marauder | Legendary Creature — Goblin Human Villain | | |
| SPM | 81 | J. Jonah Jameson | Legendary Creature — Human Citizen | | |
| SPM | 82 | Masked Meower | Creature — Spider Cat Hero | | |
| SPM | 83 | Maximum Carnage | Enchantment — Saga | | |
| SPM | 84 | Molten Man, Inferno Incarnate | Legendary Creature — Elemental Villain | | |
| SPM | 85 | Raging Goblinoids | Creature — Goblin Berserker Villain | | |
| SPM | 86 | Romantic Rendezvous | Sorcery | | |
| SPM | 87 | Shadow of the Goblin | Enchantment | | |
| SPM | 88 | Shock | Instant | | |
| SPM | 89 | Shocker, Unshakable | Legendary Creature — Human Rogue Villain | | |
| SPM | 90 | Spider-Gwen, Free Spirit | Legendary Creature — Spider Human Hero | | |
| SPM | 91 | Spider-Islanders | Creature — Spider Horror Citizen | | |
| SPM | 92 | Spider-Punk | Legendary Creature — Spider Human Hero | | |
| SPM | 93 | Spider-Verse | Enchantment | | |
| SPM | 94 | Spinneret and Spiderling | Legendary Creature — Spider Human Hero | | |
| SPM | 95 | Stegron the Dinosaur Man | Legendary Creature — Dinosaur Villain | | |
| SPM | 96 | Superior Foes of Spider-Man | Creature — Human Rogue Villain | | |
| SPM | 97 | Taxi Driver | Creature — Human Pilot | | |
| SPM | 98 | Wisecrack | Instant | | |
| SPM | 99 | Damage Control Crew | Creature — Human Citizen | | |
| SPM | 100 | Ezekiel Sims, Spider-Totem | Legendary Creature — Spider Human Advisor | | |
| SPM | 101 | Grow Extra Arms | Instant | | |
| SPM | 102 | Guy in the Chair | Creature — Human Advisor | | |
| SPM | 103 | Kapow! | Sorcery | | |
| SPM | 104 | Kraven's Cats | Creature — Cat Villain | | |
| SPM | 105 | Kraven's Last Hunt | Enchantment — Saga | | |
| SPM | 106 | Lizard, Connors's Curse | Legendary Creature — Lizard Villain | | |
| SPM | 107 | Lurking Lizards | Creature — Lizard Villain | | |
| SPM | 108 | Miles Morales // Ultimate Spider-Man | Legendary Creature — Human Citizen Hero | | |
| SPM | 109 | Pictures of Spider-Man | Artifact | | |
| SPM | 110 | Professional Wrestler | Creature — Human Warrior Performer | | |
| SPM | 111 | Radioactive Spider | Creature — Spider | | |
| SPM | 112 | Sandman, Shifting Scoundrel | Legendary Creature — Sand Elemental Villain | | |
| SPM | 113 | Scout the City | Sorcery | | |
| SPM | 114 | Spider-Ham, Peter Porker | Legendary Creature — Spider Boar Hero | | |
| SPM | 115 | Spider-Man, Brooklyn Visionary | Legendary Creature — Spider Human Hero | | |
| SPM | 116 | Spider-Rex, Daring Dino | Legendary Creature — Spider Dinosaur Hero | | |
| SPM | 117 | Spiders-Man, Heroic Horde | Legendary Creature — Spider Hero | | |
| SPM | 118 | Strength of Will | Instant | | |
| SPM | 119 | Supportive Parents | Creature — Human Citizen | | |
| SPM | 120 | Terrific Team-Up | Instant | | |